Metabolites significantly contributing to the separation of liver, brain and serum 1H NMR profiles of uninfected control Balb/C mice from mice infected with P. chabaudi at peak infection or three weeks post-clearance of the parasite.

The loading weights (p) of the original variable of the PCA scores (for the relevant PC, see result) are mentioned for each metabolite. The difference across the two classes were further subjected to univariate analysis (*p∼/#PKeys- DMG: Dimethylglycine, PCH: Phosphorylcholine, L-DOPA: L-3,4-dihydroxyphenylalanine, BA: Bile acids, 2-HI: 2-hydroxyisovaleric acid, NAG: N-acetylglutamate, GDA: Guanidoacetate, MAA: Methylacetoacetate, ACH: Acetylcholine, OAA: Oxaloacetate, u/c: Unconfirmed.针对每种代谢物，均标注了其主成分分析（Principal Component Analysis, PCA）得分原始变量的载荷权重（p），相关主成分详见结果。两类样本间的差异进一步开展单变量分析（*p∼/#PKeys-），各物质缩写与对应全称如下：DMG：二甲基甘氨酸（Dimethylglycine），PCH：磷酸胆碱（Phosphorylcholine），L-DOPA：L-3,4-二羟基苯丙氨酸（L-3,4-dihydroxyphenylalanine），BA：胆汁酸（Bile acids），2-HI：2-羟基异戊酸（2-hydroxyisovaleric acid），NAG：N-乙酰谷氨酸（N-acetylglutamate），GDA：胍乙酸（Guanidoacetate），MAA：甲基乙酰乙酸（Methylacetoacetate），ACH：乙酰胆碱（Acetylcholine），OAA：草酰乙酸（Oxaloacetate），u/c：未确认（Unconfirmed）。