Risk of treatment failure associated with occurrences of mutant alleles from DHPS, DHFR, and in combination.

1��F��ailure = (LPF, LCF, ETF); ��S��uccess = (ACPR).2Percent failure (no. failures/row total).3Relative risk of failure associated with mutant AA (relative to wild AA as reference) [RR = failure probability (mutant)/failure probability (wild)].4Confidence interval (for RR).5The presence of 164L of PfDHFR and 540E PfDHPS.1. 失败类别（Failure）涵盖LPF、LCF、ETF三类；成功类别（Success）涵盖ACPR一类。2. 失败百分比：失败例数与所在行总例数的比值。3. 以野生型氨基酸为参照时，突变氨基酸（Amino Acid, AA）对应的失败相对风险[相对风险（RR）= 突变体失败概率/野生型失败概率]。4. 相对风险的置信区间。5. 恶性疟原虫二氢叶酸还原酶（PfDHFR）的164L位点与恶性疟原虫二氢蝶酸合酶（PfDHPS）的540E位点的存在情况。