A randomized controlled safety and feasibility trial of floatation-REST in anxious and depressed individuals

Background: Reduced Environmental Stimulation Therapy via floatation (floatation- REST) is a behavioral intervention designed to attenuate exteroceptive sensory input to the nervous system. Prior studies in anxious and depressed individuals demonstrated that single sessions of floatation-REST are safe, well-tolerated, and associated with an acute anxiolytic and antidepressant effect that persists for over 48 hours. However, the feasibility of using floatation-REST as a repeated intervention in anxious and depressed populations has not been well-investigated.
Methods: In this single-blind safety and feasibility trial, 75 individuals with anxiety and depression were randomized to complete six sessions of floatation-REST in different formats: pool-REST (weekly 1-hour float sessions), pool-REST preferred (float sessions with flexibility of duration and frequency), or an active comparator (chair- REST; weekly 1-hour sessions in a Zero Gravity chair). Feasibility (primary outcome) was ass..., , , # General Information

1\. Title of Dataset: A randomized controlled safety and feasibility trial of floatation-REST in anxious and depressed individuals

2\. Author Information

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A. Principal Investigator Contact Information

Name: Sahib Khalsa, M.D., Ph.D.

Institution: Laureate Institute for Brain Research

Address: 6565 S Yale Ave. Tulsa, OK 74136

Email: [e-mail]
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3\. Date of data collection: February 2019 - October 2021

4\. Geographic location of data collection: Laureate Institute for Brain Research, Tulsa, OK

5\. Information about funding sources that supported the collection of the data: This research was supported by an award from the National Center for Complimentary and Integrative Health (R34AT009889). The authors were also supported by the National Institute of Mental Health (R01MH127225, K23MH112949 to SSK), National Institute of General Medical Sciences Center Grant Award Number (1P20GM121312 to MPP, JSF, SSK), and The William K. Warren ...

背景：漂浮式减感疗法（floatation-REST）是一种旨在减弱神经系统对外界感觉输入的行为干预手段。既往针对焦虑与抑郁人群的研究显示，单次漂浮式减感疗法安全且耐受性良好，可产生持续48小时以上的急性抗焦虑与抗抑郁效应。然而，针对焦虑抑郁人群重复实施漂浮式减感疗法的可行性，目前尚未得到充分探究。
方法：本项单盲安全性与可行性试验中，75名焦虑抑郁患者被随机分组，完成6次不同形式的漂浮式减感疗法：泳池式漂浮减感疗法（pool-REST，每周1小时漂浮疗程）、个性化泳池式漂浮减感疗法（pool-REST preferred，时长与频次可灵活调整的漂浮疗程），以及阳性对照疗法——座椅式漂浮减感疗法（chair-REST，每周在零重力椅（Zero Gravity Chair）中进行1小时疗程）。可行性（主要结局指标）经评估……
# 通用信息

1. 数据集名称：针对焦虑抑郁人群的漂浮式减感疗法随机对照安全性与可行性试验

2. 作者信息

A. 主要研究者联系方式
姓名：萨希卜·哈尔萨（Sahib Khalsa），医学博士、哲学博士
所属机构：大脑研究桂冠研究所（Laureate Institute for Brain Research）
地址：美国俄克拉荷马州塔尔萨市南耶鲁大道6565号，邮编74136
电子邮箱：[e-mail]

3. 数据采集时间：2019年2月—2021年10月

4. 数据采集地点：美国俄克拉荷马州塔尔萨市大脑研究桂冠研究所

5. 数据采集资助信息：本研究获美国国家补充与整合健康中心（National Center for Complimentary and Integrative Health）资助（项目编号：R34AT009889）。作者团队还获得了美国国家精神卫生研究所（SSK获资助项目编号：R01MH127225、K23MH112949）、美国国家普通医学科学研究所中心资助项目（MPP、JSF、SSK获资助项目编号：1P20GM121312）以及威廉·K·沃伦相关项目的支持。