Data underlying the publication: Translation-driven temporal control for intertwined protein assembly

This dataset contains data collected during correlated single-molecule force spectroscopy and multi-color confocal laser scanning spectroscopy experiments at AMOLF, as part of Katharina Till's PhD Thesis project. The objective of the project behind this data was to use disome selective ribosome profiling (DiSP) to detect co-translational assembly of BTB domain proteins in vivo and optical tweezers are to study folding and assembly transitions for individual monomers and dimers in vitro. The data included in this data set has been organised per figure of the corresponding to be published publication. The excel sheet contains several tabs containing the underlying data to the figures they are named after. The data is being made public both to act as supplementary data for publications and the PhD thesis of Katharina Till and in order for other researchers to use this data in their own work.

本数据集收录了AMOLF开展的关联单分子力谱学与多色共聚焦激光扫描光谱学实验所获取的数据，属于凯瑟琳娜·蒂尔（Katharina Till）博士学位论文研究项目的一部分。本数据集依托的研究项目目标为：采用二体选择性核糖体图谱（disome selective ribosome profiling, DiSP）在体内检测BTB结构域蛋白的共翻译组装，并利用光镊技术在体外研究单个单体与二聚体的折叠及组装转变过程。本数据集收录的数据已按照对应待发表论文中的各图进行整理分类，配套的Excel表格包含多个工作表，每个工作表均以其所对应的数据图命名，存储对应图表的原始数据。本次公开本数据集，既是为了作为凯瑟琳娜·蒂尔的博士学位论文及相关发表论文的补充数据，也是为了便于其他研究人员将其用于自身的研究工作。