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Impact of aging on cell-to-cell transcriptional variability during immune stimulation

ChEBI2016-07-21 更新2026-07-12 收录

免疫衰老

细胞转录异质性

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-4888 数据链接链接失效反馈

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资源简介：

Impact of aging on cell-to-cell transcriptional variability during immune stimulation

应用场景：

创建时间：

2016-07-21

免疫衰老

性选择

Age-related decline in immune activity is referred to as immunosenescence and has been observed for both the adaptive immune response of vertebrates and the innate immune system of invertebrates. Sinc

DataONE2012-03-30 更新160

Brain transcriptome from WT and CD300f-/- mouse

免疫衰老

小鼠模型

CD300f immune receptor contributes to healthy aging by regulating inflammaging, metabolism and cognitive decline

NIAID Data Ecosystem60

Immune phenotype of the CD4+ T cells in the aged lymphoid organs and lacrimal glands

免疫衰老

泪腺免疫学

Aging is associated with a massive infiltration of T lymphocytes in the lacrimal gland. . Among the non-Tregs, we also found a significant increase in the levels of EOMESmed/high, TbetnegIFN-𝛄+ and C

NIAID Data Ecosystem50

Unbiased pyrosequencing of human immunoglobulin mRNA repertoires defines onset of immune senescence

免疫衰老

多样性分析

The adaptive immune system protects from foreign and potentially dangerous antigens by generating specific antibody responses. The vast variety of immunoglobulin (Ig) paratopes for antigen recognition

NIAID Data Ecosystem90

Immunophenotypical analysis of the main lymphocyte subsets involved in immunosenescence.

免疫衰老

白细胞亚群分析

AResults are expressed as mean percentage of T helper and T cytotoxic lymphocytes ± S.E.M (standard error of the mean). BP values <0.05 are reported.

NIAID Data Ecosystem50