Histological characterization of 3-methyl-cholanthrene-induced sarcomas.

1Tumors were classified according to their morphology as spindle, pleomorphic or round cell sarcomas. In some cases, multiple morphologic phenotypes were present in the same tumor.2Local Infiltration was rated as follows: 0 = no tumor infiltration; 1 = minimal tumor infiltration in the surrounding muscle; 2 = massive tumor infiltration.3Necrosis was rated as follows: 0 = no necrosis; 1 = minimal areas of necrosis; 2 = large areas of necrosis.4p53 staining was rated as follows: 0 = no staining; 1 = faint staining in less than 50% of the cells; 2 = strong staining in less than 50% of the cells; 3 = strong staining in more than 50% of the cells. ND = not done.