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Engineering a robust Escherichia coli W platform for scalable production of flavonoid-O-glucosides

NIAID Data Ecosystem2026-05-10 收录

黄酮类糖苷微生物合成

代谢工程

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP585485 数据链接链接失效反馈

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资源简介：

Optimization of sucrose metabolism through adaptive laboratory evolution (ALE) and targeted metabolic engineering to reroute glucose metabolism to UDPG.

应用场景：

创建时间：

2025-12-30

代谢工程

菌株筛选优化

Additional file 1. Plasmid pWF14 sequence.

DataCite Commons2022-09-08 更新130

Additional file 3 of Farnesyl pyrophosphate compartmentalization in the green microalga Chlamydomonas reinhardtii during heterologous (E)-α-bisabolene production

生物化学

代谢工程

Additional file 3. Calculation of bisabolene titers, yields, and rates for all mutants created in this work as shown in Additional file 11: Fig. S1 and Figs. 2, 3, and 4.

DataCite Commons2022-09-15 更新70

Table 1_Targeted UDP-glucose ceramide glucosyltransferase stable overexpression induces a metabolic switch improving cell performance at high cell density.xlsx

病毒载体生产工艺优化

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BackgroundViral vectors such as adeno-associated viruses (AAVs) and virus-like particles (VLPs) are critical tools in gene therapy, typically produced using transient gene expression (TGE). Intensific

NIAID Data Ecosystem20

MOESM1 of A design–build–test cycle using modeling and experiments reveals interdependencies between upper glycolysis and xylose uptake in recombinant S. cerevisiae and improves predictive capabilities of large-scale kinetic models

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系统生物学

Additional file 1. Stoichiometry of used reactions and the corresponding mass balances.

NIAID Data Ecosystem70

Identification of Absidia orchidis steroid 11β-hydroxylation system and its application in engineering Saccharomyces cerevisiae for one-step biotransformation to produce hydrocortisone

类固醇生物合成

代谢工程

Purpose: In order to identify genes for 11β-hydroxylase CYP5311B2 and associated redox partners CPR and cytochrome b5 in filamentous fungus Absidia orchidis AS3.65 Methods: Strand-specific RNA-seq lib

NIAID Data Ecosystem50

Engineering a robust Escherichia coli W platform for scalable production of flavonoid-O-glucosides

资源简介：

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