遇见数据集

raw and preprocessed data included to the paper "Striatum-projecting prefrontal cortex neurons support working memory maintenance"

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Zenodo2023-10-18 更新2026-05-26 收录
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This Dataset includes matlab variables containing all raw and preprocessed data 1) fiber photometry experiments (GCaMP and GFP) 2) miniscope experiments 3) optogenetics experiments 4) DLC video analysis for photometry recording, optogenetic inhibition ArchT, optogenetic activation ChR2, optogenetic activation ChR2 + MK801, control experiments for optogenetic inhibition and activation 5) Source Data Files for all main and supplementary Figures collected for the paper "Striatum-projecting prefrontal cortex neurons support working memory maintenance" Maria Wilhelm1,2,6, Yaroslav Sych1,7, Aleksejs Fomins1,2, José Luis Alatorre Warren1,8, Christopher Lewis1, Laia Serratosa Capdevila1, Roman Boehringer3, Elizabeth A. Amadei3, Benjamin Grewe2,3,4, Eoin C. O'Connor5, Benjamin J. Hall5,9, Fritjof Helmchen1,2,4* 1Brain Research Institute, University of Zurich, 8057 Zurich, Switzerland. 2Neuroscience Center Zurich, University of Zurich and ETH Zurich, 8057 Zurich, Switzerland. 3Institute of Neuroinformatics, University of Zurich and ETH Zurich, 8057 Zurich, Switzerland. 4University Research Priority Program (URPP) Adaptive Brain Circuits in Development and Learning (AdaBD), University of Zurich, Zurich, Switzerland 5Neuroscience & Rare Diseases, Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland. 6Present address: Institute for Neuroscience, ETH Zurich, 8057 Zurich, Switzerland. 7Present address: Institute of Cellular and Integrative Neuroscience, CNRS, University of Strasbourg, Strasbourg, France. 8Present address: Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo 0317, Norway. 9Present address: Circuit Biology Department, H. Lundbeck A/S, Valby, Denmark. These authors contributed equally: Maria Wilhelm, Yaroslav Sych *email: helmchen@hifo.uzh.ch

本数据集包含存储所有原始与预处理数据的Matlab变量,涵盖以下内容: 1) 光纤光度测量(fiber photometry)实验(包含GCaMP与GFP相关实验) 2) 微型内窥镜成像(miniscope)实验 3) 光遗传学(optogenetics)实验 4) 针对如下实验的DLC视频分析(DeepLabCut视频分析):光度记录实验、光遗传抑制ArchT实验、光遗传激活ChR2实验、光遗传激活ChR2联合MK801给药实验,以及光遗传抑制与激活的对照实验 5) 所有主图与补充图的源数据文件 本数据集为论文"Striatum-projecting prefrontal cortex neurons support working memory maintenance"所采集,作者及单位信息如下: Maria Wilhelm¹,²,⁶, Yaroslav Sych¹,⁷, Aleksejs Fomins¹,², José Luis Alatorre Warren¹,⁸, Christopher Lewis¹, Laia Serratosa Capdevila¹, Roman Boehringer³, Elizabeth A. Amadei³, Benjamin Grewe²,³,⁴, Eoin C. O'Connor⁵, Benjamin J. Hall⁵,⁹, Fritjof Helmchen¹,²,⁴ ¹ 苏黎世大学脑研究所,瑞士苏黎世 8057 ² 苏黎世大学与苏黎世联邦理工学院苏黎世神经科学中心,瑞士苏黎世 8057 ³ 苏黎世大学与苏黎世联邦理工学院神经信息学研究所,瑞士苏黎世 8057 ⁴ 苏黎世大学大学研究优先项目(URPP)"发育与学习中的适应性脑回路"(AdaBD),瑞士苏黎世 ⁵ 罗氏制药研究与早期开发部,罗氏创新中心巴塞尔,霍夫曼-拉罗氏有限公司,瑞士巴塞尔 ⁶ 现任职单位:苏黎世联邦理工学院神经科学研究所,瑞士苏黎世 8057 ⁷ 现任职单位:法国斯特拉斯堡大学斯特拉斯堡细胞与整合神经科学研究所CNRS,法国斯特拉斯堡 ⁸ 现任职单位:奥斯陆大学脑与认知终身变化中心,挪威奥斯陆 0317 ⁹ 现任职单位:H. Lundbeck A/S回路生物学部,丹麦瓦比 共同第一作者:Maria Wilhelm与Yaroslav Sych 通讯作者:Fritjof Helmchen 通讯邮箱:helmchen@hifo.uzh.ch

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创建时间:
2023-10-09
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