Combinatorial knockout of RARα, RARβ, and RARγ completely abrogates transcriptional responses to retinoic acid in murine embryonic stem cells
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE112412
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All-trans retinoic acid (ATRA) alters gene expression in CCE WT embryonic stem cells, but has no effect on gene expression in RAR-deficient TKO cells (devoid of Retinoic Acid Receptors α, β, and γ) Murine Embryonic Stem Cells (WT and RAR-deficient TKO cells) were treated with vehicle (ETOH) or all-trans retinoic acid (ATRA, 1uM) and expression profiling was performed by RNAseq
创建时间:
2019-03-19



