Multivariate Cox regression analysis for overall survival and disease-free survival in hepatocellular carcinoma patients.

Abbreviations: OS, overall survival; DFS, disease-free survival; AFP, á-fetoprotein; HR, hazard ratio. Variables significantly associated with OS and DFS upon univariate Cox regression analysis were included in the multivariate analysis. Variables considered for OS analysis were TNM stage, AFP level, albumin level, SIRT1 expression, c-Myc expression, and p53 expression. Variables considered for DFS analysis were TNM stage, AFP level, albumin level, histologic grade, SIRT1 expression, c-Myc expression, and p53 expression.缩写说明：OS为总生存期（overall survival）；DFS为无病生存期（disease-free survival）；AFP为甲胎蛋白（á-fetoprotein）；HR为风险比（hazard ratio）。经单变量Cox回归分析筛选出与OS和DFS显著相关的变量，纳入多变量分析。用于OS分析的变量包括TNM分期、AFP水平、白蛋白水平、SIRT1表达、c-Myc表达及p53表达。用于DFS分析的变量包括TNM分期、AFP水平、白蛋白水平、组织学分级、SIRT1表达、c-Myc表达及p53表达。