RNA sequencing of RAW264.7 with or without Sal-B and LPS addition

Autologous fat grafting (AFG), although an appealing approach to repair soft tissue defects, has various complications. Excessive inflammation at the transplant site is one of the main reasons for the poor effect of fat transplantation and occurrence of complications. Our previous study proved that Salvia miltiorrhiza can enhance fat graft survival. Salvianolic acid B (Sal-B) is the most abundant and bioactive water-soluble compound in Salvia miltiorrhiza and has anti-inflammatory effects on other diseases. Therefore, we hypothesized that salvianolic acid B could improve the effect of fat grafts by inhibiting inflammation. Overall design: Examination of R264.7 RNA sequencing comparing the LPS(10ng/ml)+Sal-B addition(50µmol/L) group[LPS+50], LPS(10ng/ml) group[LPS+0] and control group[NC]