Refseq Test Subsets for Frame Classification with and without Errors

These test files extend the 'Refseq datasets for training frame classification' dataset. It provided the original test file and three variations containing erroneous sequences to simulate realistic data. The data is based on randomly selected viral and bacterial genomes and the human193(GRCh38.p13) reference genome which was downloaded from GenBank. From each original nucleic acid sequence, we created multiple patches of length 300 in all possible reading frames using a sliding window on the initial sequence and its reversed complement. The data is stored in the FASTA format according to the following convention:<br> <br> &gt;{ID}_subsequence{patch index}_frame{frame index}|{class marker}|{frame index}<br> sequence<br> <br> with<br> <br> ID - denotes the ReSeq accession of the original sequence in the Refseq dataset.<br> sequence - nucleic acid sequence patch of length 300 or 250<br> patch_index - denotes the starting triplet of the given patch within the original sequence or reverse complemented sequence (i.e. 3*patch_index is the starting index of frame 0 in the original sequence)<br> class marker - indicates the taxonomic domain<br> 0 - virus<br> 1 - bacteria<br> 2 - human / mammal<br> frame index - indicates the reading frame<br> 0 - on-frame<br> 1 - shifted by one<br> 2 - shifted by two<br> 3 - reverse complemented<br> 4 - shifted by one and reverse complemented<br> 5 - shifted by two and reverse complemented Each file contains 212.618 patches per frame.本测试文件拓展了用于训练帧分类的Refseq数据集（Refseq datasets for training frame classification）。该数据集提供了原始测试文件与三份包含错误序列的变体文件，用于模拟真实场景下的数据。本数据集的数据来源于随机选取的病毒、细菌基因组，以及从GenBank（GenBank）下载的人类193（GRCh38.p13）参考基因组。针对每条原始核酸序列，我们通过滑动窗口在初始序列及其反向互补序列上，以所有可能的读码框（reading frame）生成长度为300的多个序列片段。数据遵循以下规范以FASTA（FASTA）格式存储： >{ID}_subsequence{patch index}_frame{frame index}|{class marker}|{frame index} 序列 其中各字段含义如下： ID - 指代Refseq数据集中原始序列的RefSeq登录号； sequence - 长度为300或250的核酸序列片段； patch_index - 表示该序列片段在原始序列或反向互补序列中的起始三联体位置（即3*patch_index为原始序列中读码框0的起始索引）； class marker - 表示分类学域，对应规则为：0=病毒，1=细菌，2=人类/哺乳动物； frame index - 表示读码框类型，对应规则为：0=正向读码框，1=偏移1个碱基，2=偏移2个碱基，3=反向互补序列，4=偏移1个碱基并反向互补，5=偏移2个碱基并反向互补。 每个文件每个读码框包含212618个序列片段。