Motifs enriched in hotspots.

CpG-rich motifs are strongly enriched in canine recombination hotspots. Motifs were detected by comparing DNA sequences within 4,759 hotspots to the same number of coldspots, having matched for CpG content and SNP density. P-values are adjusted for multiple testing using the Bonferroni correction.富含CpG的基序（CpG-rich motif）在犬重组热点中显著富集。通过将4759个重组热点区域内的DNA序列与数量相同、CpG含量和单核苷酸多态性（Single Nucleotide Polymorphism, SNP）密度相匹配的重组冷点区域的DNA序列进行比对，即可检测得到此类基序。P值通过邦费罗尼（Bonferroni）校正完成多重检验校正。