Acral melanoma - Male, 69 - Tissue image [9200729571539741]

This is the histopathological image of SKIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 69Clinical description: 0,9 x 1,3 x 0,2 cm black lesion of nail of big toe of foot.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: NEVI AND MELANOMASDiagnosis: Acral melanomaResult of the histopathological examination: Acral melanoma: spindled cells, Clark III, Breslow 1,3 mm, mitotic index 4mitoses/1mm2, TILs-NON-BRISK. Melan A+, HMB45+, SOX10+, Ki-67 15%.Sample:Material: FFPECollecting method: Excision of lesionsTopography: SKINOrgan: SKINTissue: Toe nailType of staining: positive/IHCStaining: Not applicableAntibody: SOX-10Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk

本数据集为格但斯克医科大学（Medical University Gdańsk）采集并存入ZMDL-GUMED的皮肤组织样本的组织病理学图像。该样本图像采用Pannoramic 250 3DHistech玻片扫描仪（20倍放大倍率）拍摄，并存储为DICOM格式。

患者、样本及诊断详细信息如下：
患者：
年龄：69岁
临床描述：足部大脚趾指甲处存在0.9×1.3×0.2 cm的黑色病变
性别：男性
诊断分类：ICD-O_3.2分类，分类编码为NEVI AND MELANOMAS（痣与黑色素瘤）
最终诊断：肢端黑色素瘤
组织病理学检查结果：肢端黑色素瘤，梭形细胞，Clark分级Ⅲ级，Breslow厚度1.3 mm，核分裂指数为4个核分裂象/1mm²，肿瘤浸润淋巴细胞（Tumor Infiltrating Lymphocytes, TILs）-非高危型；免疫组化标记结果：Melan A阳性、HMB45阳性、SOX10阳性，Ki-67增殖指数为15%。

样本详情：
样本材质：福尔马林固定石蜡包埋（Formalin-Fixed Paraffin-Embedded, FFPE）样本
采集方式：病灶切除术
病变部位：皮肤（SKIN）
所属器官：皮肤
组织来源：趾甲
染色类型：免疫组化（Immunohistochemistry, IHC）阳性
染色方案：不适用
所用抗体：SOX-10

技术参数与设备：
成像设备：Pannoramic 250 3DHistech玻片扫描仪
镜头倍率：20倍
数据来源机构：格但斯克医科大学（Medical University Gdańsk）