首页/数据集/Additional file 2 of PACAP–Sirtuin3 alleviates cognitive impairment through autophagy in Alzheimer’s disease

Additional file 2 of PACAP–Sirtuin3 alleviates cognitive impairment through autophagy in Alzheimer’s disease

NIAID Data Ecosystem2026-05-01 收录

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https://figshare.com/articles/dataset/Additional_file_2_of_PACAP_Sirtuin3_alleviates_cognitive_impairment_through_autophagy_in_Alzheimer_s_disease/26633070 数据链接链接失效反馈

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资源简介：

Additional file 2. The detailed mRNA data.

应用场景：

创建时间：

2023-10-27

阿尔茨海默病机制

神经退行性疾病基因表达分析

To delineate the mechanism by which hTFAM suppresses AD pathology in the neuron model of AD, we first performed microarray analyses using using RNAs prepared from PS1P117L and wild-type neurons. Next,

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ABCA7 deficiency causes neuronal dysregulation by altering mitochondrial lipid metabolism

阿尔茨海默病机制

线粒体代谢

ABCA7 loss-of-function variants are associated with increased risk of Alzheimer's disease (AD). Using ABCA7 knockout human iPSC models generated with CRISPR/Cas9, we investigated the impacts of ABCA7

NIAID Data Ecosystem20

Data Sheet 1_Western diet-induced visceral adipose tissue inflammation promotes Alzheimer’s disease pathology via microglial activation in a mouse model.docx

阿尔茨海默病机制

饮食诱导神经炎症

IntroductionWestern diet (WD)-induced visceral adipose tissue (VAT) inflammation is characterized by adipocyte hypertrophy, hypoxia, and apoptosis. Epididymal white adipose tissue (eWAT), a representa

NIAID Data Ecosystem00

The cryo-EM structure of AV-45 bound type3 amyloid beta 42 fibril.

蛋白质结构解析

阿尔茨海默病机制

The cryo-EM structure of AV-45 bound type3 amyloid beta 42 fibril. Descriptor: P3(40) Authors: Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D. Deposit date: 2023-08-15 Release date: 2024-08-21 Last modified: 2025

Protein Data Bank Japan2025-07-02 更新20

Table_1_Benign Regulation of the Astrocytic Phospholipase A2-Arachidonic Acid Pathway: The Underlying Mechanism of the Beneficial Effects of Manual Acupuncture on CBF.DOC

阿尔茨海默病机制

针刺调控脑血流

BackgroundThe astrocytic phospholipase A2 (PLA2)-arachidonic acid (AA) pathway is crucial in understanding the reduction of cerebral blood flow (CBF) prior to cognitive deterioration. In complementary

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Additional file 2 of PACAP–Sirtuin3 alleviates cognitive impairment through autophagy in Alzheimer’s disease

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