Cytokine-mediated differentiation reflects genome-wide loss of a uSTAT transcriptional program

ChEBI2016-01-05 更新2026-07-12 收录

JAK-STAT信号通路

免疫细胞分化

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-70697 数据链接链接失效反馈

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Cytokine-mediated differentiation reflects genome-wide loss of a uSTAT transcriptional program

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2016-01-05

Materials for reproducibility for " Systematic investigation of JAK-STAT characteristics in proximity to disease-associated and ClinVar benign genetic variants found in the All of Us and COSMIC database "

JAK-STAT信号通路

遗传变异

Data for the manuscript " Systematic investigation of JAK-STAT characteristics in proximity to disease-associated and ClinVar benign genetic variants found in the All of Us and COSMIC database "

DataCite Commons2026-02-04 更新70

ZEB1 Promotes Pathogenic Th1 and Th17 Cells Differentiation in Autoimmune Disease

免疫细胞分化

自身免疫疾病机制

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem60

Histone architecture of stem-cell memory T cells reveals progressive remodeling of epigenetic landscape in antigen-experienced CD8 T cells. Mus musculus

细胞表观遗传学

免疫细胞分化

We investigated the genomic landscape of histone modifications in antigen-experienced CD8+ T cells. Using a ChIP-Seq approach coupled with global gene expression profiling [GSE67825], we generated gen

NIAID Data Ecosystem20

SMAD4 impedes conversion of NK cells into ILC1-like cells by curtailing non-canonical TGFb signaling (mouse data sets). Mus musculus

免疫细胞分化

TGFb信号通路

Among the features that distinguish type 1 innate lymphoid cells (ILC1s) from NK cells is a gene signature indicative of TGFb-family cytokine imprinting. To assess the impact of TGFb family cytokines

NIAID Data Ecosystem70

Additional file 7 of Single-cell transcriptomics highlights immunological dysregulations of monocytes in the pathobiology of COPD

单细胞转录组学

免疫细胞分化

Additional file 7: Dataset 5. Genes dynamically expressed during CD14+ classical monocyte-to-CD14+ intermediate monocyte differentiation, related to Fig. S3M and S3N, in which the top 250 genes based

Figshare2022-12-20 更新40

Cytokine-mediated differentiation reflects genome-wide loss of a uSTAT transcriptional program

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