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Transcriptomic changes in HCT116 cells after KAT2A knockout

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE246881
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We were interested in transcriptional changes after depletion of histone acetyltransferase KAT2A in human colorectal cancer. Therefore, we utilized HCT116 cells as model, and analyzed global alterations of gene expression. RNA-Sequencing from HCT116 cells stably expressing Cas9-GFP after transduction with either a sgRNA targeting Luciferase (control) or human KAT2A. Experiment was performed in biologically independent triplicates.
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2024-11-01
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