ABSTRACT Protein misfolding diseases are usually associated with deposits of single “key” proteins that somehow drive the pathology; β-amyloid and hyperphosphorylated tau accumulate in Alzheimer's dis
1The number of mice developing clinical signs of prion disease divided by the original number of inoculated mice is shown in parentheses. 2Inoculations performed in Telling lab. 3Inoculations performe
ABSTRACT: Bovine spongiform encephalopathy (BSE), caused by an infectious prion, emerged in the 1980s in Europe as a new disease in cattle and, since then, several actions are being taken for its pre