Composite clinical outcome score.*
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*The score was devised pre hoc by consensus opinion among the investigators. We assigned greatest significance to weight gain, due to its leading clinical importance in response to TB treatment [57]–[61], and its reliable objectivity. The selected cut-off of weight gain [57]. The lung function cut-offs were guided by knowledge of test repeatability (accuracy) and plausible improvements in FEV1 during the given time frame [38].
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2015-12-02



