Composite clinical outcome score.*

*The score was devised pre hoc by consensus opinion among the investigators. We assigned greatest significance to weight gain, due to its leading clinical importance in response to TB treatment [57]–[61], and its reliable objectivity. The selected cut-off of weight gain [57]. The lung function cut-offs were guided by knowledge of test repeatability (accuracy) and plausible improvements in FEV1 during the given time frame [38].*该评分系研究者于试验前通过专家共识法制定。鉴于体重增加在结核病（Tuberculosis, TB）治疗应答中具有核心临床重要性[57]–[61]，且其客观可靠，我们赋予其最高权重。所选定的体重增加截断值参考自文献[57]。肺功能截断值的设定则依据检测重复性（准确性）及给定时间框架内一秒用力呼气容积（Forced Expiratory Volume in 1 second, FEV1）的合理改善幅度相关研究结论[38]。