Changes in CD4+ T-cell percentages and weight-for-age z-scores after ART initiation by regimen.

EFV: efavirenz; NVP: nevirapine; SE: standard error.aResults shown are from linear mixed effects models with random intercept, exchangeable correlation structure and robust standard error estimation. Interaction terms between EFV and time were included to determine whether trajectories of the outcomes differed between children receiving EFV or NVP. For CD4+ T-cell percentage, a spline term was added at 6 months as trajectories were not linear over time.bAdjusted for hemoglobin, weight-for-age z-score, and age at ART initiation.cAdjusted for hemoglobin, CD4+ T-cell percentage, weight-for-age z-score, and age at ART initiation.EFV（依非韦伦，efavirenz）；NVP（奈韦拉平，nevirapine）；SE（标准误，standard error）。a. 本研究结果来自采用随机截距、可交换相关结构及稳健标准误估计的线性混合效应模型。为明确接受EFV或NVP治疗的儿童其结局轨迹是否存在差异，模型纳入了EFV与时间的交互项。针对CD4+ T细胞百分比，由于其随时间的变化轨迹并非线性，故额外纳入了6个月处的样条项。b. 校正因素包括血红蛋白、年龄别体重Z评分（weight-for-age z-score）及抗反转录病毒治疗（Antiretroviral Therapy, ART）启动年龄。c. 校正因素包括血红蛋白、CD4+ T细胞百分比、年龄别体重Z评分及抗反转录病毒治疗启动年龄。