Rates and hazard ratios of CVD associated with eGFR from fitting a Cox regression model.

(a) Adjusted for age, gender mode of HIV transmission, ethnicity and calendar year of baseline(b) Adjusted for smoking, diabetes mellitus,previous AIDS diagnosis, blood pressure lowering drugs,lipid lowering drugs, total cholesterol, blood glucose levelsand high density lipoprotein cholesterol(c) Adjusted for ART-status, baseline CD4, CD8, nadir CD4, baseline HIV-RNA and co-infection with hepatitis B/C(d) Adjusted for factors in footnotes a-c.Rates and hazard ratios of CVD associated with eGFR from fitting a Cox regression model.(a) 校正混杂因素包括年龄、性别、HIV传播途径、种族及基线日历年度 (b) 校正混杂因素包括吸烟史、糖尿病、既往艾滋病诊断史、降压药物、调脂药物、总胆固醇、血糖水平及高密度脂蛋白胆固醇 (c) 校正混杂因素包括抗逆转录病毒治疗（Antiretroviral Therapy, ART）状态、基线CD4细胞计数、基线CD8细胞计数、CD4细胞谷值、基线HIV-RNA水平及乙型/丙型肝炎合并感染 (d) 校正脚注a至c所列的混杂因素。 本研究通过拟合Cox比例风险回归模型，得到与估算肾小球滤过率（estimated glomerular filtration rate, eGFR）相关的心血管疾病（Cardiovascular Disease, CVD）发生率及风险比。