官方服务：
资源简介：
Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells (Affymetrix)
应用场景：
创建时间：
2025-01-24
相关数据集
Chen et al 2019 "iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition"
Raw Western blot and luciferase assay data to support the experimental results presented in the publication by Chen et al 2019 entitled "iASPP mediates p53 selectivity through a modular mechanism fine
NIAID Data Ecosystem90
Global analysis of p53-regulated transcription reveals its direct targets and unexpected regulatory mechanisms (GRO-Seq). Homo sapiens
GRO-seq of HCT116 cells treated with Nutlin to activate p53 Overall design: HCT116 cells were treated with Nutlin or DMSO for 1 hour
NIAID Data Ecosystem40
Genomewide analysis of the human p53 transcriptional network unveils a lncRNA tumor suppressor signature (expression)
We report the application of high-throughput sequencing to performed the p53 regulated trancriptome in HCT116 colon cancer cells treated with the DNA damage 5FU. To study the direct targets of p53 we
NIAID Data Ecosystem30
Global genomic profiling of p53-regulated genes. Mus musculus
p53 is a critical tumor suppressor and works as a stress-induced transcription factor to induce target genes mediating apoptosis, cell cycle arrest and senescence or other responses. To gain new insig
NIAID Data Ecosystem60
Gene expression in human lymphoblastoid cell-line GM12878 in response to doxorubicin treatment. Homo sapiens
To determine if induced p53 binding is associated with gene expression in genome-wide. We examined mRNA levels with the Affymetrix Human Exon 1.0 ST platform in human lymphoblastoid GM12878 cells trea
NIAID Data Ecosystem40
