Supplementary data - Clinical and histopathologic features differentiating acute generalized exanthematous pustulosis and pustular psoriasis: a retrospective series

Supplementary Table 2: Clinical findings in acute generalized exanthematous pustulosis and pustular psoriasis.

Supplementary Figure 2: Pustular psoriasis. A: Subcorneal pustular dermatitis with irregular epidermal hyperplasia (H&E, 48x magnification). B: CD161 highlights numerous dermal lymphocytes; a threshold of 10 positive cells per punch biopsy was significantly associated with pustular psoriasis (CD161, 200x magnification).

Supplementary Figure 3: Acute generalized exanthematous pustulosis. A: Erythroderma and monomorphous pustules following hydroxychloroquine. B: Widespread blistering following cefepime, prompting consideration of toxic epidermal necrolysis. C: Distal purpura. D: Mucosal involvement with erosions on the hard palate following administration of clindamycin.

补充表2：急性泛发性发疹性脓疱病（acute generalized exanthematous pustulosis）与脓疱性银屑病的临床特征。

补充图2：脓疱性银屑病。A：伴不规则表皮增生的角层下脓疱性皮炎（苏木精-伊红（hematoxylin-eosin, H&E）染色，放大48倍）。B：CD161染色标记大量真皮淋巴细胞；每例钻孔活检标本中10个阳性细胞的阈值与脓疱性银屑病显著相关（CD161染色，放大200倍）。

补充图3：急性泛发性发疹性脓疱病。A：羟氯喹给药后出现红皮症及单形性脓疱。B：头孢吡肟给药后出现广泛性水疱，需考虑中毒性表皮坏死松解症（toxic epidermal necrolysis, TEN）。C：远端紫癜。D：克林霉素给药后出现硬腭糜烂伴黏膜受累。