Additional file 2: of Diet-induced remission in chronic enteropathy is associated with altered microbial community structure and synthesis of secondary bile acids

Table S1. OTUs with differential abundances between samples of healthy dogs and dogs with CE at day 0 (Healthy vs CE day 0). Table S2. OTUs with differential abundances between day 0-samples of diet responsive dogs and non-diet responsive dogs. Table S3. Genera with differential abundances between samples of day 14 and day 0 (day 14 versus day 0) for diet responsive dogs. Table S4. OTUs with differential abundances between samples of day 14 and day 0 for diet responsive dogs (day 14 versus day 0). Table S5. OTUs with differential abundances between samples of day 14 and day 0 (day 14 versus day 0) for non-diet responsive dogs. Table S6. Differentially abundant pathways between day 14 and day 0 after diet treatment from metagenomic analysis for diet-responsive dogs (fold-change &gt; 1.5 and P-value &lt; 0.05). Table S7. Comparisons of bile acids in samples at different timepoints for diet responsive dogs. Table S8. Spearman correlations between abundance of OTUs and concentration of Bile acids in diet responsive dogs. Table S9. Spearman correlations between bile acids and bile salt hydolases (BSHs) in diet-responsive dogs (P &lt; 0.05). (XLSX 135 kb)补充表S1：健康犬与慢性肠病（CE）犬第0天样本间丰度存在差异的操作分类单元（Operational Taxonomic Unit，OTU）（健康组vs CE组第0天）。补充表S2：饮食应答犬与无饮食应答犬第0天样本间丰度存在差异的OTU。补充表S3：饮食应答犬第14天与第0天样本间丰度存在差异的菌属（第14天vs第0天）。补充表S4：饮食应答犬第14天与第0天样本间丰度存在差异的OTU（第14天vs第0天）。补充表S5：无饮食应答犬第14天与第0天样本间丰度存在差异的OTU（第14天vs第0天）。补充表S6：饮食应答犬经饮食干预后，宏基因组分析显示第14天与第0天样本间丰度存在显著差异的代谢通路（倍数变化>1.5且P值<0.05）。补充表S7：饮食应答犬不同时间点样本的胆汁酸水平比较。补充表S8：饮食应答犬中OTU丰度与胆汁酸浓度间的斯皮尔曼相关性。补充表S9：饮食应答犬中胆汁酸与胆汁盐水解酶（BSHs）间的斯皮尔曼相关性（P<0.05）。（XLSX格式，大小135 KB）