Data from: T1-weighted in vivo human whole brain MRI dataset with an ultrahigh isotropic resolution of 250 μm

We present an ultrahigh resolution in vivo human brain magnetic resonance imaging (MRI) dataset. It consists of T1-weighted whole brain anatomical data acquired at 7 Tesla with a nominal isotropic resolution of 250 μm of a single young healthy Caucasian subject and was recorded using prospective motion correction. The raw data amounts to approximately 1.2 TB and was acquired in eight hours total scan time. The resolution of this dataset is far beyond any previously published in vivo structural whole brain dataset. Its potential use is to build an in vivo MR brain atlas. Methods for image reconstruction and image restoration can be improved as the raw data is made available. Pre-processing and segmentation procedures can possibly be enhanced for high magnetic field strength and ultrahigh resolution data. Furthermore, potential resolution induced changes in quantitative data analysis can be assessed, e.g., cortical thickness or volumetric measures, as high quality images with an isotropic resolution of 1 and 0.5 mm of the same subject are included in the repository as well.

本研究公开了一套超高分辨率活体人脑磁共振成像（magnetic resonance imaging, MRI）数据集。该数据集包含一名年轻健康白种人受试者的全脑T1加权解剖成像数据，采集于7特斯拉磁场环境下，标称各向同性分辨率达250微米，扫描全程采用前瞻性运动校正技术。原始数据总量约为1.2 TB，总扫描时长共计8小时。该数据集的分辨率远超此前已发表的所有活体全脑结构成像数据集，其潜在应用之一为构建活体人脑MR图谱。公开该原始数据可推动图像重建与图像复原方法的优化升级。针对高场强及超高分辨率成像数据，其预处理与分割流程亦可得到进一步优化完善。此外，该数据集的存储库中还包含同一名受试者的1 mm、0.5 mm各向同性分辨率高质量成像数据，因此可用于评估分辨率变化对定量数据分析的潜在影响，例如皮层厚度或体积测量等分析场景。