Osteosarcoma is the most frequent bone tumor. Notwithstanding that significant medical progress has been achieved in recent years, the 5-year overall survival of osteosarcoma patients is inferior. Reg
Additional file 6: Table S5. The methylation loci and corresponding genes involved in MAPK signalling, pyruvate metabolism, glycolysis, and proteoglycan pathways.
Inhibition or genetic deletion of poly(ADP-ribose) polymerase-1 (PARP-1) is profoundly protective against a number of toxic insults in many organ systems1,2. In the brain the molecular mechanisms unde
