Gbx2 is essential for maintaining thalamic neuron identity and repressing habenular characters in the developing thalamus. Mus musculus

Using microarray, we compared the transcriptome of the wild-type and Gbx2-KO thalamus at E12.5. We show that Gbx2 promotes thalamic but inhibits habenular molecular characters. Overall design: Total RNA obtained from microdissected thalamus of wild-type and Gbx2-KO embryos at E12.5.