Expression data from patients with different stages of clear cell renal cell carcinoma

Clear cell renal cell carcinoma is the most common type among kidney cancers, accounting for 80% of all kidney cancer cases and over 30% of patients have metastases at the time disease is diagnosed. The process od epithelial-mesenchymal transition is crucial for the development and progression of cancer, and here we wanted to check the expression of genes on different stages of tumor progression, and find which of them changes significantly with increased grade. Tumor samples from patients were divided into four grades by hospital pathologists. I- grade refers to the first stage of disease, II- grade to second, III-grade to third and IV-grade to fourth. Each patients received unrepetable number. RNA extraction were performed using Eurx kit, and then microarrays were performed using Affymetrix GeneChip WT PLUS Reagent Kit.