Correlations of left ventricular systolic function indices with aortic root systolic excursion (ARSE): A cross-sectional echocardiographic study

BackgroundHeart failure (HF), is a major public health issue globally. Echocardiography is cost–effective in the diagnosis in expert hands. This study was conducted to estimate the usefulness of Aortic Root Systolic Excursion (ARSE) as a simple and accurate measure to estimate Left Ventricular (LV) function.MethodsThis was a cross-sectional echocardiographic study among adults aged ≥ 18 years, with or without heart failure, in sinus rhythm, and with no LV out–let obstruction. We studied the correlations of ARSE with some selected indices of LV Systolic Functions. We determined optimal cut–offs of ARSE in detecting LV dysfunction. We generated a simple regression equation to best estimate LV ejection fraction according to the modified Simpson method.ResultsOverall 213 echocardiograms were included from 106 males (49.8%), with mean age of the participants being 52.4 (SD: 18.3) years. The rate of LV systolic dysfunction was highest with Teicholz method (17.4%) and lowest with MAPSE method (5.2%). ARSE correlated with the LV functions. This was highest for the Simpson method (r = 0.619, pConclusionARSE correlated well with LV systolic function. The cut–off ≤ 6.5 mm suggest LV systolic dysfunction. LV Ejection Fraction was best estimated with the generic equation: LVEF (%) = 29 x In [ARSE].研究背景：心力衰竭（Heart Failure, HF）是全球范围内的重大公共卫生问题。超声心动图在专业医师操作下具备成本效益俱佳的诊断价值。本研究旨在评估主动脉根收缩移位（Aortic Root Systolic Excursion, ARSE）作为简便且精准的左心室（Left Ventricular, LV）功能评估指标的实用性。 研究方法：本研究为横断面超声心动图研究，纳入年龄≥18岁、无论是否合并心力衰竭、呈窦性心律且无左心室流出道梗阻的成人受试者。本研究分析了ARSE与若干选定的左心室收缩功能指标之间的相关性，确定了ARSE检测左心室功能障碍的最佳截断值，并构建了基于改良辛普森法的简易回归方程，以最优估算左心室射血分数（Left Ventricular Ejection Fraction, LVEF）。 研究结果：本研究共纳入213份超声心动图检查结果，其中男性受试者106例（占比49.8%），受试者平均年龄为52.4岁（标准差SD：18.3）。采用泰赫霍兹法（Teicholz method）检测的左心室收缩功能障碍发生率最高（17.4%），采用二尖瓣环收缩期位移（Mitral Annular Plane Systolic Excursion, MAPSE）法检测的发生率最低（5.2%）。ARSE与左心室功能指标存在相关性，其中以辛普森法的相关性最为显著（r=0.619, p）。 研究结论：主动脉根收缩移位（ARSE）与左心室收缩功能具有良好的相关性。当ARSE截断值≤6.5mm时，提示存在左心室收缩功能障碍。左心室射血分数可通过通用公式进行最优估算：LVEF（%）=29×ln[ARSE]。