We generated a collection of patient-derived pancreatic normal and cancer organoids. We performed whole genome sequencing, targeted exome sequencing, and RNA sequencing on organoids as well as matched

NIAID Data Ecosystem20

Adaptation to an acid microenvironment promotes pancreatic cancer organoid growth and drug resistance [acid]. Adaptation to an acid microenvironment promotes pancreatic cancer organoid growth and drug resistance [acid]

胰腺癌类器官

酸性微环境适应与耐药性

We investigated transcriptomic changes in pancreatic ductal organoids under adaptation to an acidic extracellular environment. Overall design: Wild type ("mN10"), KrasG12D ("mP4"), p53 knockout ("mP4

NIAID Data Ecosystem10

6e2605eb-9faa-4b69-bbf4-6165b901724c - samples

胰腺癌类器官

RNA测序分析

RNA sequencing of 31 pancreatic cancer organiodsEGA dataset EGAD00001005217

NIAID Data Ecosystem20

Organoids derived from pancreatic adenocarcinoma patients share morphological and genetic features with the primary tumor. Organoids derived from pancreatic adenocarcinoma patients share morphological and genetic features with the primary tumor

胰腺癌类器官

肿瘤模型相似性验证

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem20