PsPM-FSS7B: Inhibiting human aversive memory by transcranial theta-burst stimulation to primary sensory cortex

This dataset includes skin conductance response (SCR), electromygoram (EMG), and pupil size response (PSR) measurements. Also included are CS and US information, keypress responses, keypress response times and key correctness. The dataset contains data from 68 healthy unmedicated participants (34 females) participating in a classical (Pavlovian) discriminant delay fear conditioning task. Simple and complex CS are deliverd to the intermediate phalanges of the index and middle fingers of the nondominant hand. Simple stimulis are stimulations to either index or middle finger, complex stimulis are stimulations of different temporal structure to both index and middle fingers. CS intensity is set to a perceivable but not unpleasant level. US is a train of electric square pulses delivered with a constant current stimulator (Digitimer DS7A, Digitimer, Welwyn Garden City, UK) on participants' dominant forearm through a pin-cathode/ring-anode configuration. SOA betwen the CS and US is 3.5 s. The ITI is randomly determined on each trial to be 7, 9, or 11 s. The study included fear acquisition (day 1), recall and retest sessions (day 2). Participants are divided into experimental and control groups, where experimental group received continuous theta-burst stimulation on primary somatosensory cortex contralateral to the CS hand immediately prior to fear acquisition, and control group received the same stimulation to the primary somatosensory cortex ipsilateral to the CS hand. For SCR data from the acquisition session, there are 62 datasets (28 experimental, 34 control), and for PSR, 37 datasets (20 experimental, 17 control). For EMG data from the recall session, there are 52 datasets (25 experimental, 27 control). For SCR data from the retest session, there are 56 datasets (27 experimental, 39 control), and for PSR, 42 datasets (22 experimental, 20 control).本数据集包含皮肤电反应（skin conductance response, SCR）、肌电图（electromyogram, EMG）及瞳孔大小反应（pupil size response, PSR）的测量数据，同时涵盖条件刺激（conditioned stimulus, CS）与无条件刺激（unconditioned stimulus, US）信息、按键反应、按键反应时及按键正确率数据。 本数据集的受试者为68名未服用药物的健康被试（女性34名），所有被试均参与了经典（巴甫洛夫式）辨别延迟恐惧条件反射任务。 实验将简单与复杂条件刺激施加于非利手的示指与中指中节指骨：简单刺激为仅作用于示指或中指的单一刺激，复杂刺激为同时作用于示指与中指且具备不同时间结构的复合刺激。条件刺激强度设置为可被感知但不会引发不适的水平。 无条件刺激采用恒流刺激器（Digitimer DS7A, Digitimer, 英国韦林花园城），以针状阴极/环状阳极装置施加于被试利手前臂，刺激形式为连续方形电脉冲串。条件刺激与无条件刺激的刺激呈现间隔（stimulus onset asynchrony, SOA）为3.5秒。每一试次的试次间隔（inter-trial interval, ITI）随机取值为7、9或11秒。 本研究包含三个实验阶段：恐惧习得阶段（第1天）、回忆阶段与重测阶段（第2天）。被试被分为实验组与对照组：实验组在恐惧习得开始前，对与条件刺激刺激手对侧的初级躯体感觉皮层施加持续性theta爆发刺激；对照组则对与条件刺激刺激手同侧的初级躯体感觉皮层施加相同参数的刺激。 针对各阶段的不同生理数据，数据集的有效组数如下：习得阶段的皮肤电反应数据共62组（实验组28组，对照组34组），瞳孔大小反应数据共37组（实验组20组，对照组17组）；回忆阶段的肌电图数据共52组（实验组25组，对照组27组）；重测阶段的皮肤电反应数据共56组（实验组27组，对照组39组），瞳孔大小反应数据共42组（实验组22组，对照组20组）。