MOESM1 of Monitoring dynamic cytotoxic chemotherapy response in castration-resistant prostate cancer using plasma cell-free DNA (cfDNA)

Additional file 1. Patient data summary. Patient demographics in summary and in detail at baseline, PCR technical variability, cfDNA data and COSMIC IDs of SNVs. Abbreviations: PSA, prostate-specific antigen; Hgb, hemoglobin; LINE1, long interspersed nuclear elements 1, Mets = metastases, LN = lymph nodes. Offset (h) indicates sample collection time relative to treatment. G-K represent single PCR reactions, L represents pooled sample containing 10 replicate PCR reactions. Patient samples analyzed in initial screen in bold.附加文件1：患者数据汇总。内容涵盖基线时患者人口统计学特征的概要与详细信息、聚合酶链式反应（Polymerase Chain Reaction, PCR）技术变异度、循环游离DNA（circulating cell-free DNA, cfDNA）数据，以及单核苷酸变异（Single Nucleotide Variants, SNVs）的癌症体细胞突变目录（Catalogue of Somatic Mutations in Cancer, COSMIC）标识符。缩写说明：前列腺特异性抗原（prostate-specific antigen, PSA）、血红蛋白（hemoglobin, Hgb）、长散在核元件1（long interspersed nuclear elements 1, LINE1）、转移灶（metastases, Mets）及淋巴结（lymph nodes, LN）。偏移时长（h）表示样本采集时间相对于治疗的时间间隔。G-K代表单次PCR反应实验，L代表包含10次重复PCR反应的混合样本。初始筛选阶段分析的患者样本以粗体标注。