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Analysis of Calcium Spike Trains in HEK293 Cells

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Zenodo2025-07-15 更新2026-05-26 收录
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This repository contains processed calcium spike train data derived from the analysis of time-lapse fluorescence imaging of HEK293 cells stimulated with carbachol. Each experiment (named as YYYYMMDDexp#, e.g., 20240309E1) is a .csv file containing spike train features extracted from stationary sections of the recording. These files serve as input for the analysis script available at https://github.com/azzonic/calcium_spiketrains_analysis For cells displaying multiple stationary spiking sections (i.e., changes in spiking frequency during the recording), more than one file is provided with suffixes like _# (e.g., 20240309E1_3). These represent different stationary sections, analysed separately, of the same spike train from the main file. The original fluorescence traces from where stationary sections have been selected are available at 10.5281/zenodo.15705673

本仓库存储了经处理的钙峰序列(calcium spike train)数据,该数据集来源于对经卡巴胆碱(carbachol)刺激的HEK293细胞(HEK293 cells)的延时荧光成像(time-lapse fluorescence imaging)分析结果。 每个实验以YYYYMMDDexp#格式命名(示例:20240309E1),对应一个.csv格式文件,其中包含从记录的稳定放电时段中提取的峰序列特征。此类文件可作为分析脚本的输入数据,该脚本的开源地址为https://github.com/azzonic/calcium_spiketrains_analysis。 对于存在多个稳定放电时段(即记录过程中放电频率发生变化)的细胞,会提供多个带有_#后缀的文件(示例:20240309E1_3)。这些文件分别对应主文件中同一钙峰序列的不同稳定时段,已完成单独分析。 已选取稳定时段对应的原始荧光轨迹数据,可通过10.5281/zenodo.15705673获取。

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Zenodo
创建时间:
2025-07-15
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