Crystal Structure of wild-type EGFR in complex with the reversible inhibitor Sevabertinib (BAY 2927088)

Crystal Structure of wild-type EGFR in complex with the reversible inhibitor Sevabertinib (BAY 2927088) Descriptor: 1,2-ETHANEDIOL, 3-[(3-chloranyl-2-methoxy-phenyl)amino]-2-[3-[[(2~{S})-1,4-dioxan-2-yl]methoxy]pyridin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one, CHLORIDE ION, ... Authors: Hillig, R.C. Deposit date: 2025-04-16 Release date: 2025-10-15 Last modified: 2026-01-21 Method: X-RAY DIFFRACTION (2.142 Å) Cite: Sevabertinib, a Reversible HER2 Inhibitor with Activity in Lung Cancer. Cancer Discov, 16, 2026