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Functional neurons generated from T cell-derived iPSCs for neurological disease modeling

ChEBI2016-01-14 更新2026-07-12 收录

神经细胞分化

神经疾病模型

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-76832 数据链接链接失效反馈

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资源简介：

Functional neurons generated from T cell-derived iPSCs for neurological disease modeling

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创建时间：

2016-01-14

神经细胞分化

表观遗传调控

Long noncoding RNAs (lncRNAs) play a wide range roles in the epigenetic regulation of crucial biological processes, but the functions of lncRNAs in cortical development are poorly understood. Using hu

NIAID Data Ecosystem40

The expression of regional markers in neural crest cell (NCC) aggregates treated with or without retinoic acid (RA).

神经细胞分化

视黄酸靶基因

To evaluate the anterior-posterior axial identity of the NCC aggregates, we prepared aggregates treated with RA to induce posterior fates as a positive control and compared gene expression patterns am

NIAID Data Ecosystem10

Effect of OCT4 overexpression on the neural induction of human dental pulp stem cells

神经细胞分化

牙髓干细胞重编程

Stem cell-based therapy is an alternative strategy for brain repair. Various cell types have been investigated and dental pulp stem cells (DPSC) have been identified as promising candidates. These mul

NIAID Data Ecosystem00

Gene expression data from human neural stem cells (hNSCs) treated with 10 uM TCQA for 24 hours

神经细胞分化

神经发生

TCQA promoted differentiation of hNSCs at least toward the neuronal lineage and suggests the possibility of using TCQA to promote neurogenesis. When differentiation is induced by growth factor withdra

NIAID Data Ecosystem10

b-catenin Signaling Dynamics Regulate Cell Fate in Differentiating Neural Stem Cells

神经细胞分化

b-catenin信号动态

Stem cells undergo differentiation in complex and dynamic environments wherein instructive signals fluctuate on various timescales. Thus, cells must be equipped to properly respond to the timing of si

Alliance of Genome Resources00

Functional neurons generated from T cell-derived iPSCs for neurological disease modeling

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