Pseudoexfoliation syndrome in a 27-year-old patient: a case report

ABSTRACT Pseudoexfoliation syndrome is more frequent in people aged >50 yeears, and its prevalence increases with age. Few reports have described cases in younger patients, all with a history of ocular surgery, especially iris resection. Herein, we describe the case of a 27-year old man with bilateral advanced glaucoma and pseudoexfoliation material in OS. He had undergone cataract surgeries OU and a penetrating keratoplasty OD during childhood. Currently, he presented with an intraocular pressure of 40 mmHg OU. The OS showed a white flaky material in the pupillary rim and anterior capsule and a Sampaolesi line as a gonioscopic finding. Trabeculectomy was performed OU, and intraocular pressure control was achieved. Unlike other previously reported cases, this patient did not present any apparent iris manipulation in the affected eye. However, he did undergo an iridectomy in the contralateral eye. This is also the first case to be accompanied by bilateral glaucoma at the time of detection of the pseudoexfoliation material.【摘要】假性剥脱综合征（Pseudoexfoliation syndrome）好发于50岁以上人群，其患病率随年龄增长逐步升高。目前针对年轻患者的报道较为稀缺，既往报道的年轻病例均有眼科手术史，尤以虹膜切除术史最为常见。本文报告1例27岁男性患者，其罹患双侧进展期青光眼，左眼（OS, Oculus Sinister）检出假性剥脱物质。患者童年时期曾行双眼（OU, Oculus Uterque）白内障手术及右眼（OD, Oculus Dexter）穿透性角膜移植术。本次就诊时，患者双眼眼压均达40 mmHg。左眼检查可见瞳孔缘与前囊膜存在白色片状物质，房角镜检查可见桑帕奥利线（Sampaolesi line）。遂为患者行双眼小梁切除术，术后眼压得到有效控制。与既往报道的病例不同，本例患者的受累眼并无明确的虹膜操作史，但对侧眼曾接受虹膜切除术。此外，本案例亦是首次在检出假性剥脱物质的同时即伴随双侧青光眼的病例报告。