Data underlying the research on particle manipulation using hydrodynamic forcing. This dataset consist of the experimental data of a single particle deflection in a Hele-Shaw cell.

The reseach objective is to present a microfluidic approach to achieve the dynamic control of particle pathlines within a flow through microfluidic device. Our approach combines three key aspects: the design of a flow-through microfluidic flow cell with the ability to manipulate the streamlines of the flow, an optimization procedure to find a priori optimal particle path-lines, and a Proportion-Integral-Derivative-based (PID) feedback controller to provide real time control over the particle manipulations. The experimental raw images were recorded with a sCMOS camera (PCO) with a pixel pitch of 6.5 μm. The camera was mounted on a microscope (Nikon Eclipse Ti) with a 1x objective. The acquisition frequency was 5 Hz corresponding to an average in-plane displacement of 4-6 pixels between two consecutive recordings. The zip file contains the raw images and the MATLAB script used to do an experiment of a single particle deflected by only using the hydrodynamic forcing in a Hele-Shaw cell.

本研究旨在提出一种微流控方法，实现微流控装置内流场中粒子运动轨迹的动态调控。本方案整合三项核心技术环节：其一，设计可调控流场流线的直通式微流控流室（flow-through microfluidic flow cell）；其二，构建寻优流程以获取先验最优粒子运动轨迹；其三，采用基于比例-积分-微分（Proportion-Integral-Derivative, PID）的反馈控制器，实现粒子调控的实时控制。实验原始图像由sCMOS相机（PCO）采集，该相机像素间距为6.5 μm。相机搭载于尼康Eclipse Ti显微镜上，搭配1×物镜。图像采集频率为5 Hz，对应两次连续采集之间的平面内平均位移为4~6个像素。本压缩包包含原始图像以及用于开展单粒子调控实验的MATLAB脚本，该实验仅通过赫勒-肖（Hele-Shaw）流室内的流体动力强迫实现粒子偏转。