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Causality of gut bacteria Klebsiella pneumoniae to hypertension development

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE184584
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Purpose: we conducted this study to investigate whether gut K.pn is a causal factor for HTN pathogenesis and the potential mechanism Methods: Renal transcriptome changes were assessed by RNA-sequencing Results: significant upregulation of several genes related to HTN pathogenesis were observed Conclusions:These results provide evidence that the enrichment of K.pn acts as a direct contributor for hypertension pathogenesis Renal transcriptome profiles of germ-free mice and antibiotic pretreated mice receiving K.pn
创建时间:
2022-09-30
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