FAIRsharing record for: CRAM

This FAIRsharing record describes: CRAM is a sequencing read file format that is highly space efficient by using reference-based compression of sequence data and offers both lossless and lossy modes of compression. Building on early proof-of-principle for reference-based compression (Hsi-Yang Fritz, et al. (2011). Genome Res. 21:734-740), the CRAM format balances usability with compression efficiency.

本FAIRsharing记录描述如下：CRAM是一种测序读段文件格式，通过对序列数据实施基于参考序列的压缩实现极高的空间利用率，同时支持无损与有损两种压缩模式。该格式依托早期基于参考序列压缩的原理验证研究（Hsi-Yang Fritz等，2011年，《Genome Res.》21卷：734-740页），在易用性与压缩效率之间达成了良好平衡。