Model parameters for biochemical reactions.

a All rates for internal reactions were assumed to be the same as on the cell surface. Unit conversion was required (not shown) for kon and KD in internal compartments (from M-1s-1 to (#/cm2)-1s-1 for kon and from M to #/cm2 for KD) using the total volume of the specified endosomal compartment per unit surface area (See S2 Table- not assumed to be spherical). Note that all rates are effective rates; diffusion considerations are lumped into these effective rates.Model parameters for biochemical reactions.a) 所有细胞内反应的速率均假定与细胞表面反应速率一致。针对胞内区室中的缔合速率常数 (kon) 与解离平衡常数 (KD)，需基于指定内体区室单位表面积对应的总体积进行单位转换（转换过程未展示）：kon的单位从M⁻¹s⁻¹转换为(#/cm²)⁻¹s⁻¹，KD的单位从M转换为#/cm²（详见S2表——该内体不假定为球形）。请注意，所有速率均为有效速率；扩散相关考量已被整合至这些有效速率中。生化反应的模型参数。