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Gene expression analysis of pancreatic cancer organoids provides insights in tumor progression mechanisms.. Gene expression analysis of pancreatic cancer organoids provides insights in tumor progression mechanisms.

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NIAID Data Ecosystem2026-05-02 收录
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This study used strand-specific RNA-sequencing of epithelial organoid cultures of primary cells from KrasLSLG12D/+; Trp53LSLR172H/+;Pdx1-Cre (KPC) mice to study the pathways that are dysregulated during tumor progression following p53 inactivation. We profiled gene expression in 3 TR172H/+ and TR172H/LOH organoid pairs. Overall design: Strand-specific RNA-sequencing of epithelial organoid cultures of primary cells from KrasLSLG12D/+; Trp53LSLR172H/+; Pdx1-Cre (KPC) mice.

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2024-09-27
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