Iron-Catalyzed Dioxygen-Driven C–C Bond Formation: Oxidative Dearomatization of 2‑Naphthols with Construction of a Chiral Quaternary Stereocenter

Iron­(salan) complex 1 was found to catalyze the oxidative dearomatization of 1-substituted 2-naphthols with the formation of an all-carbon quaternary stereocenter in air in the presence of nitroalkanes, to afford the corresponding cyclic enones with high enantioselectivity of 88–96% ee.研究表明，铁(salan)配合物1可在空气氛围与硝基烷烃共存的条件下，催化1-取代-2-萘酚发生氧化脱芳构化反应，构建全碳季碳立体中心，以88%~96% ee的高对映选择性得到相应的环状烯酮产物。