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Gene expression profile on the penile tissue of erectile dysfunction (ED) in cavernous nerve injury (CNI) RAT model

Alliance of Genome Resources2026-08-01 收录

勃起功能障碍分子机制

海绵体神经损伤基因表达

数据链接：

https://www.ncbi.nlm.nih.gov/gds/?term=GSE31247 数据链接链接失效反馈

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We performed microarray experiment focused on theto understanding the gene signature alteration in the corporal cavernous tissue of the CNI-induced ED rat model.

应用场景：

勃起功能障碍分子机制

神经损伤动物模型

(Erectile dysfunction) ED during the radical prostatectomy (RP) treatment is caused by surgical injury of the cavernous nerve which is the final neuronal pathways of penile erection. We performed micr

NIAID Data Ecosystem40

The Role of Mechanoregulated YAP/TAZ in Erectile Dysfunction. The Role of Mechanoregulated YAP/TAZ in Erectile Dysfunction

勃起功能障碍分子机制

Yap信号通路

Phosphodiesterase type 5 inhibitors (PDE5is) are the primary therapeutic option for erectile dysfunction. However, 30% of patients do not respond to PDE5is treatment, making the quest for a new treatm

NIAID Data Ecosystem20

Molecular and spatial signatures of human and rat corpus cavernosum physio-pathological processes at single-cell resolution

单细胞空间转录组学

勃起功能障碍分子机制

The composition and cellular heterogeneity of the corpus cavernosum (CC) microenvironment has been characterized, but the spatial heterogeneity at the molecular level remains unexplored. In this study

Zenodo2024-08-23 更新10

Single-cell Transcriptome Atlas of the Human Corpus Cavernosum

单细胞转录组学

勃起功能障碍分子机制

Single-cell transcriptomes of corpus cavernosum from three males with normal erections and five organic erectile dysfunction (ED) patients. Three normal tissue samples were obtained from the tumour ma

NIAID Data Ecosystem20

Comparative transcriptome analyses of geriatric rats associate age-related erectile dysfunction with a lncRNA-miRNA-mRNA regulatory network

勃起功能障碍分子机制

RNA调控网络

This study aimed to identify putative lncRNAs that regulate age-related erectile dysfunction via transcriptome analyses, and to predict their specific regulatory routes via bioinformatics methods.

NIAID Data Ecosystem10

Gene expression profile on the penile tissue of erectile dysfunction (ED) in cavernous nerve injury (CNI) RAT model

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