Lactococcus garvieae Assembly. Lactococcus garvieae

Eclipta prostrata was recently reported to be a novel therapy for osteoporosis prevention by targeting gut microbiota. Various bacteria were isolated from wild plant samples of E. prostrata, and EP01 had significant inhibitory effects on Staphylococcus aureus and Escherichia coli. However, it is still not clear that whether the main target of E. prostrata on gut microbiota was its own pharmacodynamic substances or secondary metabolites from endophytic microorganisms. Moreover, endophytic bacteria in E. prostrata might also affected intestinal ecology by colonization into the intestinal environment. Therefore, in view of the influence of endophytic bacteria on the efficacy of TCM, screening, sequencing and analysing endophytic bacteria from TCM is a hot field in the study of pharmacodynamics, and has important research significance and application prospects