Success rates and feasibility of nasal Nitric Oxide sampling during tidal breathing and velum closure modality, using hand-held and stationary analysers in patients with primary ciliary dyskinesia, cystic fibrosis and in healthy subjects.

Hand-held nNO was measured by sampling rate of both 2 ml/s (MINO2) and 5 ml/s (MINO5). Two stationary analysers (CLD 88sp and NIOX Flex) were employed. Both non-velum closure (nVC) and velum closure (VC) results are shown. §: VC accomplished by standard manoeuvre during exhalation against resistance in a mouthpiece. The fraction of cooperative measurements and according success rates are shown for each test modality, with age and diagnoses given for uncooperative individuals. TB: Tidal Breathing, BH: Breath Hold, PCD: Primary Ciliary Dyskinesia, CF: Cystic Fibrosis, HS: Healthy Subjects.