Success rates and feasibility of nasal Nitric Oxide sampling during tidal breathing and velum closure modality, using hand-held and stationary analysers in patients with primary ciliary dyskinesia, cystic fibrosis and in healthy subjects.

Hand-held nNO was measured by sampling rate of both 2 ml/s (MINO2) and 5 ml/s (MINO5). Two stationary analysers (CLD 88sp and NIOX Flex) were employed. Both non-velum closure (nVC) and velum closure (VC) results are shown. §: VC accomplished by standard manoeuvre during exhalation against resistance in a mouthpiece. The fraction of cooperative measurements and according success rates are shown for each test modality, with age and diagnoses given for uncooperative individuals. TB: Tidal Breathing, BH: Breath Hold, PCD: Primary Ciliary Dyskinesia, CF: Cystic Fibrosis, HS: Healthy Subjects.本研究通过2 ml/s（MINO2）与5 ml/s（MINO5）两种采样流速，对手持式鼻一氧化氮（nasal nitric oxide, nNO）进行检测。本次检测采用两台固定式分析仪，型号分别为CLD 88sp与NIOX Flex。本数据集涵盖非软腭闭合（non-velum closure, nVC）与软腭闭合（velum closure, VC）两种检测模式的结果。§：软腭闭合通过呼气时对抗咬嘴阻力的标准操作流程完成。各检测模式下的配合式检测占比及对应成功率均已列出，不配合受试者的年龄与诊断信息也一并给出。其中缩写对应含义如下：TB为潮气呼吸（Tidal Breathing），BH为屏气测试（Breath Hold），PCD为原发性纤毛运动障碍（Primary Ciliary Dyskinesia），CF为囊性纤维化（Cystic Fibrosis），HS为健康受试者（Healthy Subjects）。