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Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in a closed ternary complex with the artificial base pair dDs-dPxTP

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in a closed ternary complex with the artificial base pair dDs-dPxTP Descriptor: ACETATE ION, DNA (5'-D(*AP*AP*AP*(DNU)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... Authors: Betz, K, Marx, A, Diederichs, K, Hirao, I, Kimoto, M. Deposit date: 2017-03-31 Release date: 2017-06-28 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural Basis for Expansion of the Genetic Alphabet with an Artificial Nucleobase Pair. Angew. Chem. Int. Ed. Engl., 56, 2017

本数据集为水生嗜热菌(Thermus Aquaticus)来源的DNA聚合酶I大片段与人工碱基对dDs-dPxTP形成闭合三元复合物的晶体结构。 描述项:乙酸根离子(ACETATE ION)、DNA(5'-D(*AP*AP*AP*(DNU)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3')、DNA(5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3')…… 作者:Betz K、Marx A、Diederichs K、Hirao I、Kimoto M 提交日期:2017-03-31 发布日期:2017-06-28 最后修改日期:2024-01-17 实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率1.7埃(1.7 Å) 引用文献:《使用人工碱基对扩展遗传字母表的结构基础》,发表于Angew. Chem. Int. Ed. Engl.,第56卷,2017年
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2017-03-31
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