Expectations regarding heterozygosity-fitness correlations (HFCs).

Under the general effect hypothesis, HFCs are due to genome-wide effects that should result in stronger correlations between genetic diversity at neutral loci compared to nonneutral loci. In contrast, under both the local and direct effect hypotheses, HFCs should result from selection on or near the molecular markers themselves, in which case there should be stronger correlations between fitness and genetic diversity at nonneutral loci than between fitness and genetic diversity at neutral loci.