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CLiP heterogeneity scores for PGC schizophrenia cohorts and their combination.

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Figshare2020-09-21 更新2026-04-28 收录
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Cohorts with an asterisk have had a SNP excluded which has zero variance within either the case or control cohort, which would result in an undefined correlation. P-values of scores using the liability threshold null (CLiP) are shown along with p-values using a null of zero (BUHMBOX) in parentheses. An FDR of was used for Benjamini-Hochberg analysis.

带星号的队列已剔除了在病例组或对照组队列中方差为零的单核苷酸多态性(Single Nucleotide Polymorphism, SNP),此类方差为零的SNP会导致相关性计算无定义。基于易患性阈值零假设(CLiP)得到的得分P值,与基于零值零假设得到的得分P值(标注为BUHMBOX)一并展示,后者以括号形式呈现。本次分析采用错误发现率(False Discovery Rate, FDR)开展本杰明-霍奇伯格校正分析。

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2020-09-21
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